Madeleine and Thomas are smoking blunts and watching movies when Madeleine's cat, Meowy, speaks to them in perfect English and demands their help saving the planet from certain catastrophe.
Madeleine, Thomas, and Meowy map out their plan of attack. Their roommate, Nanette, returns home from a bad day at work only to be confronted by Meowy, who then gives them their marching orders.
Madeleine, Nanette, and Thomas are dragged from their beds by Meowy to begin their quest to Bushwick in search of clues.
After a close run-in with the law, the three roommates have a chance encounter with a rebel informant cat named Buttons who gives them the dish on a new lead.
Our reluctant heroes walk right into the maw of the enemy and they find it full of temptations.
The roommates and their new friend Eloise flee the Pretty Kitty house and find themselves lost in Bed-Stuy. Thomas draws his boundaries and the ladies decide to run an errand that does not go as expected.
The team assembles, but the madness they find leads them ever closer to the mewling mastermind.
Following one final clue, Madeleine, Nanette, and Thomas find themselves in Astoria, betrayed by one of their own, and face to face with the evil Fuzzy Boots.